A team of researchers from the Brown University researchers has developed a new antibacterial coating for intravascular catheters so as to help avoid any catheter-related bloodstream infections, which is the vastly found type of hospital-acquired infection. These infections are difficult to control and can ultimately kill an individual as well. The researchers wanted to develop a coating that could kill the planktonic bacteria completely and inhibit any further colonization of bacteria on the surfaces. The polyurethane coating could be easily applied on the surfaces of products used significantly in the medical field followed by the release of a drug named auranofin in order to kill methicillin-resistant Staphylococcus aureus (MRSA) bacteria, which are commonly found as per the lab tests.
The MRSA biofilms cause the bacteria to become resilient to antimicrobial treatment which is inhibited by the coating. The combination of medicine and engineering develops a perfect solution as in the case of catheters. In the US, around 150 Million or more intravascular catheters are implanted on an annual basis, which also increases the chances of infections in 250,000 patients. About 25% of the patients die yearly due to this and in case saved have a huge hospital due to pay for.
The presently used methods have been known to release the drug payload faster, use bacterial resistant antibiotics, or retain a shorter durability time. The FDA has approved the auranofin for arthritis treatment but it has been found to be effective against MRSA and other microbes. The polymer coating contains the drug helped the catheter remain durable for a longer time without any breakage. The antibiofilm property gives it a plus point to stop resistant nature developed by the bacteria. Dr. Richard Martin and his team from Aston University discovered a new method using the medieval period technique of glass making to kill hospital infections within hours. The bioactive phosphate glass containing traces of the metallic element cobalt helped completely kill some of the deadly bacterial infections E.coli, Candida albicans, and Staphylococcus aureus.
Vanessa Boone carries a total of 7 years experience in the healthcare domain. She owns a Master’s of Medicine Degree. She bagged numerous awards by contributing in the medical field with her ground-breaking notions. Vanessa has developed her own style of working and known for accuracy in her work. She loves trekking. She visits new places whenever she gets free time.